Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin

  title={Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin},
  author={Ie-Ming Shih and Christopher J. Torrance and Lori Sokoll and Daniel Wai-Tin Chan and Kenneth W. Kinzler and Bert Vogelstein},
  journal={Nature Medicine},
There is no tool more essential to cancer research than the experimental tumor. Every therapeutic and preventative strategy uses such tumors, and tumors growing in animals are instrumental for basic studies of cancer biology. Most experimental tumors are injected subcutaneously because subsequent growth can be followed visually. However, it would often be preferable to have tumors grow internally, in an environment that more closely mimics that of naturally occurring tumors. Mice with internal… CONTINUE READING


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