Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin

@article{Shih2000AssessingTI,
  title={Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin},
  author={Ie-Ming Shih and Christopher J. Torrance and Lori Sokoll and Daniel Wai-Tin Chan and Kenneth W. Kinzler and Bert Vogelstein},
  journal={Nature Medicine},
  year={2000},
  volume={6},
  pages={711-714}
}
There is no tool more essential to cancer research than the experimental tumor. Every therapeutic and preventative strategy uses such tumors, and tumors growing in animals are instrumental for basic studies of cancer biology. Most experimental tumors are injected subcutaneously because subsequent growth can be followed visually. However, it would often be preferable to have tumors grow internally, in an environment that more closely mimics that of naturally occurring tumors. Mice with internal… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 26 references

Orthotopic and ectopic organ environments differentially influence the sensitivity of 714 NATURE MEDICINE

C. Wilmanns, D. Fan, C. A. O’Brian, C. D. Bucana, I. J. Fidler
Int. J. Cancer 52, • 2000

E.r.) 1204–1270 (w.b

D. J. Newman, C. P. Price
Tietz Textbook of Clinical Chemistry • 1999

Repetitive, noninvasive imaging of the dopamine D2 receptor as a reporter gene in living animals

MacLaren, D.C
Gene Ther • 1999

Visualizing the kinetics of tumor-cell clearance in living animals.

Proceedings of the National Academy of Sciences of the United States of America • 1999

implications for noninvasive imaging of transgene expression

Jacobs, A. et al. Functional coexpression of HSV-1 thymidine kinase, green fluorescent protein
Neoplasia 1, 154–161 • 1999

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