Assessing the validity of clinical trials.

  title={Assessing the validity of clinical trials.},
  author={Anthony K Akobeng},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={47 3},
Clinical trials use scientific methods to evaluate the effectiveness and safety of treatments or other interventions. Trials should have both internal and external validity, and a well-conducted randomised controlled trial is considered to be the most powerful tool for evaluating interventions. Systematic error (bias) and random error could threaten the internal validity of trials, and all efforts should be made to minimise these in the design, conduct, and analysis of studies. Careful… CONTINUE READING
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