Biocompatibility pathways and mechanisms for bioactive materials: The bioactivity zone
- ChemistryBioactive Materials
This essay analyzes the scientific evidence that forms the basis of bioactive materials, covering the fundamental understanding of bioactivity phenomena and correlation with the mechanisms of…
SHOWING 1-10 OF 95 REFERENCES
Residual immune response towards decellularized homografts may be highly individual
- MedicineEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Residual immunogenicity of decellularized homografts appears to exist despite almost complete cell removal, and the established dot blot method allows a semi-quantitative assessment of the individual immune response towards extracellular DHV components and potentially the possibility of preoperative homografted matching.
A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes.
- MedicineThe New England journal of medicine
In this 16-week trial involving children with type 1 diabetes, the glucose level was in the target range for a greater percentage of time with the use of a closed-loop system than with theUse of a sensor-augmented insulin pump.
Cellular Microenvironment-Sensitive Drug Eluting Coating on Intraocular Lens for Enhanced Posterior Capsular Opacification Prevention and in Vivo Biocompatibility
Posterior capsular opacification (PCO) is a common complication after cataract surgery, which often leads to a progressive decline in patient’s vision. It has been established that PCO is related t...
Clinical Opportunities for Continuous Biosensing and Closed-Loop Therapies
The current state of continuous chemical sensor development, titratable drug delivery systems, and closed-loop therapies are reviewed to identify clinically meaningful trends that, if realized, can have significant impact on medical practice and patient outcome.
Clinical use of a 180‐day implantable glucose sensor improves glycated haemoglobin and time in range in patients with type 1 diabetes†
- MedicineDiabetes, obesity & metabolism
This real‐world study evaluated the changes in glycated haemoglobin (HbA1c) and continuous glucose monitoring (CGM) metrics associated with use of the implantable 180‐day Eversense CGM System…
Comparison of Ocular Biometry Profiles in Urban and Rural Cataract Candidates in Eastern China
- MedicineJournal of ophthalmology
A profile of ocular biometric data and corneal astigmatism will be helpful in planning for intraocular lens (IOL) power calculations andAstigmatism correction in subjects in different locations is reported for the first time.
Dual drug delivery from hydrophobic and hydrophilic intraocular lenses: in-vitro and in-vivo studies.
- MedicineJournal of controlled release : official journal of the Controlled Release Society
The objective of this work was to investigate the use of IOLs as controlled release platforms of two drugs, the antibiotic moxifloxacin and the anti-inflammatory ketorolac that could advantageously substitute the usual treatment.
Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis
- Medicine, Materials ScienceBiomaterials Research
Although several functional nanomaterials have provided the innovative solid substrate for high performances, developing on-site version of biosensor that meets enough sensitivity along with high reproducibility still remains a challenge.
Evaluation of in vivo immunotoxicity for Ho3+-doped Gd2O3 nanoparticles as dual-modality nanoprobes
- Materials Science
Abstract Rare-earth-doped gadolinium-oxide (Gd2O3) nanoparticles (NPs) are increasingly used for magnetic resonance imaging (MRI) and optical imaging (OI). However, to date, the poor data of in vivo…
Exposure to gadolinium and neurotoxicity: current status of preclinical and clinical studies
No cause-effect relationship has been demonstrated in patients between brain gadolinium exposure and clinical consequences specific to neurological toxicity, as confirmed by preclinical animal and human (MR imaging and autopsy) studies.