Assessing the safety of drugs in pregnancy: the role of prospective cohort studies.

@article{Irl2000AssessingTS,
  title={Assessing the safety of drugs in pregnancy: the role of prospective cohort studies.},
  author={C. Irl and J. Hasford},
  journal={Drug safety},
  year={2000},
  volume={22 3},
  pages={169-77}
}
Since, for obvious reasons, systematic testing of the teratogenic properties of drugs in humans is not possible in the premarketing phase, the epidemiological approaches to postmarketing risk evaluation are of major importance. Cohort studies, with their prospective exposure assessment, their ability to study even exposure to drugs not commonly used in pregnancy, and their ability to monitor both adverse and beneficial fetal outcomes, seem to be the most promising study type from a… CONTINUE READING