Assessing the quality of reports of randomized clinical trials: is blinding necessary?

@article{Jadad1996AssessingTQ,
  title={Assessing the quality of reports of randomized clinical trials: is blinding necessary?},
  author={Alejandro Alex R Jadad and R Andrew Moore and Dawn Carroll and Crispin C Jenkinson and Dustin Reynolds and David J Gavaghan and H. J. McQuay},
  journal={Controlled clinical trials},
  year={1996},
  volume={17 1},
  pages={1-12}
}
It has been suggested that the quality of clinical trials should be assessed by blinded raters to limit the risk of introducing bias into meta-analyses and systematic reviews, and into the peer-review process. There is very little evidence in the literature to substantiate this. This study describes the development of an instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research and its use to determine the effect of rater blinding on the assessments of… CONTINUE READING
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