Assessing the presence of abnormal regulation of cortisol secretion by membrane hormone receptors: in vivo and in vitro studies in patients with functioning and non-functioning adrenal adenoma.

@article{DallAsta2004AssessingTP,
  title={Assessing the presence of abnormal regulation of cortisol secretion by membrane hormone receptors: in vivo and in vitro studies in patients with functioning and non-functioning adrenal adenoma.},
  author={Chiara Dall'Asta and Emilia Ballare and Giovanna Mantovani and Bruno Ambrosi and Anna Spada and Laura Barbetta and P Colombo and Pietro Travaglini and Paola Loli and Paolo Beck-Peccoz},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2004},
  volume={36 8},
  pages={578-83}
}
Regulation of cortisol secretion by aberrant hormone receptors may play a role in the pathogenesis of ACTH-independent Cushing's syndrome. In this study, the topic was evaluated by combining in vivo and in vitro approaches. Cortisol responses to various stimuli (standard meal, GnRH + TRH, cisapride, vasopressin, glucagon) were assessed in 6 patients with… CONTINUE READING