Assessing the patterns of linkage disequilibrium in genic regions of the human genome.

@article{Sun2011AssessingTP,
  title={Assessing the patterns of linkage disequilibrium in genic regions of the human genome.},
  author={Peng Sun and Ruijie Zhang and Yongshuai Jiang and Xing Ling Wang and Jin Li and Hongchao Lv and Guoping Tang and Xiaodan Guo and Xianwen Meng and Haikun Zhang and Ruimin Zhang},
  journal={The FEBS journal},
  year={2011},
  volume={278 19},
  pages={3748-55}
}
We used the genotyping data generated by the International HapMap Project to study the patterns of linkage disequilibrium (LD) in human genic regions. LD patterns for 11,998 genes from 11 HapMap populations were identified by analyzing the distribution of haplotype blocks. The genes were prioritized using LD levels. The results showed that there were… CONTINUE READING