Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming

Eric C. Donny, George E. Bigelow, S Walsh
Published 2003 in Psychopharmacology

Abstract

Impaired ability to refrain from initiating cocaine-taking is a central feature of cocaine dependence and an important target for behavioral and pharmacological interventions. One potential trigger of cocaine-taking is exposure to cocaine (i.e. priming). Here, we report a model of human cocaine self-administration that quantifies the ability to refrain from… (More)

DOI: 10.1007/s00213-003-1655-z

Enadoline and butorphanol: evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans.

S L Walsh, B Geter-Douglas, E C Strain, G E Bigelow
The Journal of pharmacology and experimental…
2001

Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming

Abstract

Topics

3 Figures and Tables

Cited By

Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine.

Impaired insight in cocaine addiction: laboratory evidence and effects on cocaine-seeking behaviour.

Alternative reinforcer response cost impacts cocaine choice in humans.

Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms.

Choosing Under the Influence: A Drug-Specific Mechanism by Which the Setting Controls Drug Choices in Rats

Multiple ambiguities in the measurement of drug craving.

Gene x abstinence effects on drug cue reactivity in addiction: multimodal evidence.

Prior access to a sweet is more protective against cocaine self-administration in female rats than in male rats.

Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes.

The prevalence of alcohol and drugs in sampled oral fluid is related to sample volume.

References

Choosing to take cocaine in the human laboratory: effects of cocaine dose, inter-choice interval, and magnitude of alternative reinforcement.

Enadoline and butorphanol: evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans.

Influence of an alternative reinforcer on human cocaine self-administration.

Acute effects of oral cocaine on inhibitory control of behavior in humans.

Effects of saline substitution on responding and plasma corticosterone in rats trained to self-administer different doses of cocaine.

Influence of individual differences and chronic fluoxetine treatment on cocaine-seeking behavior in rats

Personality, stress, and social support in cocaine relapse prediction.

The impact of impulsivity on cocaine use and retention in treatment.

Stress-induced relapse to heroin and cocaine seeking in rats: a review.

Cocaine-seeking produced by experimenter-administered drug injections: dose-effect relationships in rats

Slides referencing similar topics

Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming

Abstract

Topics

3 Figures and Tables

Cited By

Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine.

Impaired insight in cocaine addiction: laboratory evidence and effects on cocaine-seeking behaviour.

Alternative reinforcer response cost impacts cocaine choice in humans.

Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms.

Choosing Under the Influence: A Drug-Specific Mechanism by Which the Setting Controls Drug Choices in Rats

Multiple ambiguities in the measurement of drug craving.

Gene x abstinence effects on drug cue reactivity in addiction: multimodal evidence.

Prior access to a sweet is more protective against cocaine self-administration in female rats than in male rats.

Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes.

The prevalence of alcohol and drugs in sampled oral fluid is related to sample volume.

References

Choosing to take cocaine in the human laboratory: effects of cocaine dose, inter-choice interval, and magnitude of alternative reinforcement.

Enadoline and butorphanol: evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans.

Influence of an alternative reinforcer on human cocaine self-administration.

Acute effects of oral cocaine on inhibitory control of behavior in humans.

Effects of saline substitution on responding and plasma corticosterone in rats trained to self-administer different doses of cocaine.

Influence of individual differences and chronic fluoxetine treatment on cocaine-seeking behavior in rats

Personality, stress, and social support in cocaine relapse prediction.

The impact of impulsivity on cocaine use and retention in treatment.

Stress-induced relapse to heroin and cocaine seeking in rats: a review.

Cocaine-seeking produced by experimenter-administered drug injections: dose-effect relationships in rats

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