Assessing the incremental value of diagnostic and prognostic markers: a review and illustration.


BACKGROUND New markers may improve prediction of diagnostic and prognostic outcomes. We review various measures to quantify the incremental value of markers over standard, readily available characteristics. METHODS Widely used traditional measures include the improvement in model fit or in the area under the receiver operating characteristic (ROC) curve… (More)
DOI: 10.1111/j.1365-2362.2011.02562.x


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