Assessing the efficiency of multiple sequence alignment programs

@inproceedings{Pais2013AssessingTE,
  title={Assessing the efficiency of multiple sequence alignment programs},
  author={Fabiano Sviatopolk-Mirsky Pais and Patr{\'i}cia De C{\'a}ssia Ruy and Guilherme Oliveira and Roney Coimbra},
  booktitle={Algorithms for Molecular Biology},
  year={2013}
}
BackgroundMultiple sequence alignment (MSA) is an extremely useful tool for molecular and evolutionary biology and there are several programs and algorithms available for this purpose. Although previous studies have compared the alignment accuracy of different MSA programs, their computational time and memory usage have not been systematically evaluated. Given the unprecedented amount of data produced by next generation deep sequencing platforms, and increasing demand for large-scale data… CONTINUE READING

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