Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.

@article{Andrews2017AssessingTS,
  title={Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.},
  author={Peter W. Andrews and Uri Ben-David and Nissim Benvenisty and Peter John Coffey and Kevin C Eggan and Barbara B Knowles and Andras D Nagy and Martin F Pera and Benjamin Eithan Reubinoff and Peter J Rugg-Gunn and Glyn N. Stacey},
  journal={Stem cell reports},
  year={2017},
  volume={9 1},
  pages={
          1-4
        }
}
Pluripotent stem cells may acquire genetic and epigenetic variants during culture following their derivation. At a conference organized by the International Stem Cell Initiative, and held at The Jackson Laboratory, Bar Harbor, Maine, October 2016, participants discussed how the appearance of such variants can be monitored and minimized and, crucially, how their significance for the safety of therapeutic applications of these cells can be assessed. A strong recommendation from the meeting was… CONTINUE READING
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