Assessing the Impacts of Mutations to the Structure of COVID-19 Spike Protein via Sequential Monte Carlo

  title={Assessing the Impacts of Mutations to the Structure of COVID-19 Spike Protein via Sequential Monte Carlo},
  author={Samuel W. K. Wong},
  journal={arXiv: Biomolecules},
Proteins play a key role in facilitating the infectiousness of the 2019 novel coronavirus. A specific spike protein enables this virus to bind to human cells, and a thorough understanding of its 3-dimensional structure is therefore critical for developing effective therapeutic interventions. However, its structure may continue to evolve over time as a result of mutations. In this paper, we use a data science perspective to study the potential structural impacts due to ongoing mutations in its… Expand

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