Assessing reproducibility by the within-subject coefficient of variation with random effects models.

@article{Quan1996AssessingRB,
  title={Assessing reproducibility by the within-subject coefficient of variation with random effects models.},
  author={Hui Quan and W J Shih},
  journal={Biometrics},
  year={1996},
  volume={52 4},
  pages={1195-203}
}
In this paper we consider the use of within-subject coefficient of variation (WCV) for assessing the reproducibility or reliability of a measurement. Application to assessing reproducibility of biochemical markers for measuring bone turnover is described and the comparison with intraclass correlation is discussed. Both maximum likelihood and moment confidence intervals of WCV are obtained through their corresponding asymptotic distributions. Normal and log-normal cases are considered. In… CONTINUE READING

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