Assessing phage therapy against Pseudomonas aeruginosa using a Galleria mellonella infection model.

@article{Beeton2015AssessingPT,
  title={Assessing phage therapy against Pseudomonas aeruginosa using a Galleria mellonella infection model.},
  author={Michael L. Beeton and Diana R Alves and Mark C. Enright and A Toby A Jenkins},
  journal={International journal of antimicrobial agents},
  year={2015},
  volume={46 2},
  pages={196-200}
}
The Galleria mellonella infection model was used to assess the in vivo efficacy of phage therapy against laboratory and clinical strains of Pseudomonas aeruginosa. In a first series of experiments, Galleria were infected with the laboratory strain P. aeruginosa PAO1 and were treated with varying multiplicity of infection (MOI) of phages either 2h post-infection (treatment) or 2h pre-infection (prevention) via injection into the haemolymph. To address the kinetics of infection, larvae were bled… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 18 references

Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases • 2010
View 1 Excerpt

Amoxicillin and specific bacteriophage can be used together for eradication of biofilm of Klebsiella pneumoniae B5055

M Bedi, V Verma, S. Chhibber
World J Microbiol Biotechnol • 2009
View 1 Excerpt

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…