Assessing lymphocyte functions in neonates for revealing abnormal prenatal development of the immune system.

@article{Neubert2000AssessingLF,
  title={Assessing lymphocyte functions in neonates for revealing abnormal prenatal development of the immune system.},
  author={Reinhard T Neubert and Idolina Delgado and Jessie R Webb and Martin Brauer and Joachim Wolfram Dudenhausen and Hans Helge and Diether Neubert},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  year={2000},
  volume={20 4},
  pages={171-93}
}
Because it is difficult to assess prenatally induced functional deficits of the human immune system, we developed an ex vivo method for differentiation and maturation of peripheral lymphocytes of newborn, preferentially using umbilical cord blood. Many lymphocyte subsets of newborn infants are "immature" with respect to defined surface receptors. An example… CONTINUE READING