Assessing graphene nanopores for sequencing DNA.

@article{Wells2012AssessingGN,
  title={Assessing graphene nanopores for sequencing DNA.},
  author={David B. Wells and Maxim Belkin and Jeffrey Comer and Aleksei Aksimentiev},
  journal={Nano letters},
  year={2012},
  volume={12 8},
  pages={4117-23}
}
Using all-atom molecular dynamics and atomic-resolution Brownian dynamics, we simulate the translocation of single-stranded DNA through graphene nanopores and characterize the ionic current blockades produced by DNA nucleotides. We find that transport of single DNA strands through graphene nanopores may occur in single nucleotide steps. For certain pore geometries, hydrophobic interactions with the graphene membrane lead to a dramatic reduction in the conformational fluctuations of the… CONTINUE READING
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