Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups

  title={Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups},
  author={Joanna L. Mountain and Neil Risch},
  journal={Nature Genetics},
  volume={36 Suppl 1},
Descriptions of human genetic variation given thirty years ago have held up well, considering the substantial accrual of DNA sequence data in the interim. Most importantly, estimates of between-group genetic variation have remained relatively low. Despite the low average level of between-group variation, clusters recently inferred from multilocus genetic data coincide closely with groups defined by self-identified race or continental ancestry. This correspondence implies that genetic factors… 

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The use of racial, ethnic, and ancestral categories in human genetics research.

T careful investigations of the biological, environmental, social, and psychological attributes associated with these categories will be an essential component of cross-disciplinary research into the origins, prevention, and treatment of common diseases, including those diseases that differ in prevalence among groups.

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  • M. BeaumontR. Nichols
  • Biology
    Proceedings of the Royal Society of London. Series B: Biological Sciences
  • 1996
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