Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays.

@article{Kim2004AssessingEA,
  title={Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays.},
  author={In Young Kim and Jae Ho Shin and Hyung Sik Kim and Su Jung Lee and Il Hyun Kang and Tae Sung Kim and Hyun Ju Moon and Kwang Sik Choi and Aree Moon and Soon Young Han},
  journal={The Journal of reproduction and development},
  year={2004},
  volume={50 2},
  pages={
          245-55
        }
}
Pyrethroid insecticides are among the most commonly used classes of insecticides worldwide, but their endocrine disrupting activities remain unclear. Therefore, in the present study, we examined the estrogenic activities of pyrethroid insecticides in E-screen and competition binding assays. In addition, we measured estrogen receptor (ER) protein and pS2 mRNA levels in human breast cancer cells (MCF-7 BUS) to clarify the mechanism of their estrogenicity. Seven pyrethroid insecticides… CONTINUE READING

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HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Assessing estrogenicity by quantitating 255 IN VITRO ESTROGENICITY OF PYRETHROIDS the expression levels of endogenous estrogenregulated genes

M Jorgensen, B Vendelbo, NE Skakkebaek, H. Leffers
  • Environ Health Perspect
  • 2000
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Estrogenicity of organophosphorus and pyrethroid pesticides.

  • Journal of toxicology and environmental health. Part A
  • 2002
VIEW 2 EXCERPTS