Assessing diversity: immune reconstitution and T-cell receptor BV spectratype analysis following stem cell transplantation.

@article{Peggs2003AssessingDI,
  title={Assessing diversity: immune reconstitution and T-cell receptor BV spectratype analysis following stem cell transplantation.},
  author={Karl S. Peggs and Stephanie Verfuerth and Shirley D'sa and Kwee Yong and Stephen Mackinnon},
  journal={British journal of haematology},
  year={2003},
  volume={120 1},
  pages={154-65}
}
T-cell receptor (TCR) BV spectratyping provides information concerning immune reconstitution complementary to that derived from monoclonal antibody analysis of surface antigen expression. However, the most appropriate way to analyse and represent these data, the number of subfamilies that should be analysed, and the effects of CD4/8 ratio on observed diversity, remain unclear. A diversity scoring system was developed based on analysis of 11 cord blood (CB) and 12 normal adult BV spectratypes… CONTINUE READING

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