Assessing contamination levels of Laguna Lake sediments (Philippines) using a contact assay with zebrafish (Danio rerio) embryos.

@article{Hallare2005AssessingCL,
  title={Assessing contamination levels of Laguna Lake sediments (Philippines) using a contact assay with zebrafish (Danio rerio) embryos.},
  author={Arnold V. Hallare and Thomas Kosmehl and Tobias Schulze and Henner Hollert and Heinz-R K{\"o}hler and Rita Triebskorn},
  journal={The Science of the total environment},
  year={2005},
  volume={347 1-3},
  pages={
          254-71
        }
}
The present study investigated the suitability of a sediment contact assay using zebrafish (Danio rerio) embryos to evaluate the degree of lake sediment contamination. As endpoints, developmental parameters (mortality, abnormality, heart rate, and hatching rate) as well as stress protein responses (hsp 70 levels) in the developing embryos were recorded during a 96-h exposure. Fertilized zebrafish eggs were exposed to both the whole as well as organic extract concentrations prepared from… Expand
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