Assessing chemokine co-receptor usage in HIV

@article{Coakley2005AssessingCC,
  title={Assessing chemokine co-receptor usage in HIV},
  author={E. Coakley and C. Petropoulos and J. Whitcomb},
  journal={Current Opinion in Infectious Diseases},
  year={2005},
  volume={18},
  pages={9–15}
}
Purpose of review HIV entry into cells is mediated through sequential interactions between HIV envelope proteins (Env) and two cellular molecules: CD4 and a co-receptor, typically either CCR5 or CXCR4. Co-receptor preference has been associated with other viral traits; specifically, CXCR4-tropic viruses have been associated with increased host cell pathogenicity and more rapid progression of disease. Recently, much attention has been focused on the development of CCR5 and CXCR4 antagonists as… Expand
162 Citations
CCR5 Antagonists: Host-Targeted Antivirals for the Treatment of HIV Infection
  • 116
Current tests to evaluate HIV-1 coreceptor tropism
  • 47
Resistance to CCR5 antagonists
  • M. Westby
  • Biology, Medicine
  • Current opinion in HIV and AIDS
  • 2007
  • 20
HIV‐1 coreceptor preference is distinct from target cell tropism: a dual‐parameter nomenclature to define viral phenotypes
  • 92
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 52 REFERENCES
Preferential suppression of CXCR4-specific strains of HIV-1 by antiviral therapy.
  • 85
  • PDF
Co-receptor antagonists as HIV-1 entry inhibitors
  • 80
HIV-1 coreceptor usage, transmission, and disease progression.
  • 118
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection.
  • 240
  • PDF
The entry of entry inhibitors: A fusion of science and medicine
  • J. Moore, R. Doms
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
  • 279
  • PDF
...
1
2
3
4
5
...