Assessing appropriateness of antimicrobial therapy: in the eye of the interpreter.

  title={Assessing appropriateness of antimicrobial therapy: in the eye of the interpreter.},
  author={Daryl D Depestel and Edward H. Eiland and Katherine T. Lusardi and Christopher J Destache and R C Mercier and Patrick M McDaneld and Kenneth C. Lamp and Thomas J Chung and Elizabeth D. Hermsen},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={59 Suppl 3},
To address the increase of drug-resistant bacteria and widespread inappropriate use of antimicrobials, many healthcare institutions have implemented antimicrobial stewardship programs to promote appropriate use of antimicrobials and optimize patient outcomes. However, a consensus definition of appropriate use is lacking. We conducted a multicenter observational study to compare 4 definitions of appropriateness--a study site-specific definition, use supported by susceptibility data, use… CONTINUE READING
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