Assessing Susceptibility from Early-Life Exposure to Carcinogens

@inproceedings{Barton2005AssessingSF,
  title={Assessing Susceptibility from Early-Life Exposure to Carcinogens},
  author={Hugh A. Barton and V. James Cogliano and Lynn Flowers and Larry Valcovic and R. Woodrow Setzer and Tracey J. Woodruff},
  booktitle={Environmental health perspectives},
  year={2005}
}
Cancer risk assessment methods currently assume that children and adults are equally susceptible to exposure to chemicals. We reviewed available scientific literature to determine whether this was scientifically supported. We identified more than 50 chemicals causing cancer after perinatal exposure. Human data are extremely limited, with radiation exposures showing increased early susceptibility at some tumor sites. Twenty-seven rodent studies for 18 chemicals had sufficient data after… CONTINUE READING

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