Assessing Resource Demands during Sentence Processing in Parkinson's Disease

@article{Grossman2002AssessingRD,
  title={Assessing Resource Demands during Sentence Processing in Parkinson's Disease},
  author={Murray Grossman and Christine Lee and Jennifer Morris and Matthew B. Stern and Howard I. Hurtig},
  journal={Brain and Language},
  year={2002},
  volume={80},
  pages={603-616}
}
Patients with Parkinson's disease (PD) have sentence comprehension difficulty, but it is unclear whether this is due to a deficit in grammatical processing or to an executive resource limitation. To assess grammatical processing in PD while minimizing task-related demands, PD patients and healthy control subjects performed a word detection procedure that assesses sensitivity to grammatical agreements in sentences in an "on-line" fashion. With this technique, we found that control subjects and… Expand
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References

SHOWING 1-10 OF 43 REFERENCES
Sentence comprehension in Parkinson's disease: The role of attention and memory
TLDR
There are multiple sources of cognitive difficulty underlying PD patients' sentence comprehension impairment, and specific grammatical, semantic, and attentional mechanisms are identified as significant contributors toPD patients' overall sentence comprehension. Expand
Cognitive Resource Limitations during Sentence Comprehension in Parkinson's Disease
TLDR
It is found that a subgroup of PD patients with impaired sentence comprehension at baseline did not differ from random in their accuracy understanding all types of sentences during the more demanding (recognition span) condition and also had difficulty understanding the most complex sentence during the less demanding (finger tapping) condition. Expand
Dopamine supports sentence comprehension in Parkinson’s Disease
TLDR
Dopamine supports the executive resources contributing to sentence comprehension in PD, and performance on an independent measure of verbal working memory correlated only with comprehension of grammatically complex sentences during levodopa supplementation. Expand
Investigating the basis for the sentence comprehension deficit in Parkinson's disease
Abstract We sought to determine whether patients with idiopathic Parkinson's disease (PD) have sentence comprehension impairments because of a compromised grammatical parser or difficulty attendingExpand
Strategies in Comprehension of Relative Clauses by Parkinsonian Patients
TLDR
The overall picture of the findings suggests that PD patients process sentences with complex thematic roles and semantic reversibility on a heuristic and not on an algorithmic basis, a type of behavior assumed to be associated with frontal lobe dysfunction. Expand
Algorithmic and heuristic strategies in comprehension of complement clauses by patients with Parkinson's disease
TLDR
Language ability in patients with idiopathic Parkinson's disease and normal control subjects matched on age, sex, education and socioeconomic status (SES) was investigated and syntax with semantic constraints was the most effective independent variable to classify PD patients and NC subjects into two distinct groups. Expand
Impaired Comprehension of Raising-to-Subject Constructions in Parkinson's Disease
TLDR
This paper describes an experiment which shows that roughly half of nondemented patients with Parkinson's disease have impaired comprehension of subject- to-subject and object-to-subject raising constructions, but have normal comprehension of the counterpart constructions. Expand
Sentence comprehension and praxis deficits in Parkinson's disease
TLDR
It is concluded that language and gestural processing impairments are frequent in patients with PD. Expand
A central executive deficit in patients with Parkinson's disease.
TLDR
Whether Parkinson's disease produces deficits in the coordinating and integrating function of the central executive component of Baddeley's working memory model is examined to examine whether this model is advantageous in providing a rich conceptual basis to explore and characterise cognitive abilities in patients with Parkinson’s disease. Expand
A capacity approach to syntactic comprehension disorders: making normal adults perform like aphasic patients
Abstract This paper presents a theory of syntactic comprehension disorders in aphasic patients. In line with some recent proposals, the current theory assumes that aphasic patients still possess theExpand
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