Assessing Expression of MUC 1 and ZAG Protein Biomarkers in Prostate Biopsies Improves Prediction of Adverse Pathology Following Radical Prostatectomy

@inproceedings{Durrani2015AssessingEO,
  title={Assessing Expression of MUC 1 and ZAG Protein Biomarkers in Prostate Biopsies Improves Prediction of Adverse Pathology Following Radical Prostatectomy},
  author={Nazish Durrani and Mark Waldron and Catherine A Cherry and Laurence M. Harewood and Mark Frydenberg and John Gregor Pedersen and John P. Mills},
  year={2015}
}
Objectives: To determine whether assessing expression of MUC1 and ZAG proteins in prostate biopsies, by immunohistochemistry, improves prediction of radical prostatectomy histopathology, which in turn predicts longer-term outcomes. Methods: We studied 231 consecutive patients managed by two experienced urologic surgeons (MF, LH). Each patient had prostate biopsies revealing cancer followed by a radical prostatectomy. Expression of MUC1 and ZAG in biopsy tissue was assessed by… CONTINUE READING
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