Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels

@inproceedings{Mehrban2014AssessingCR,
  title={Assessing Cellular Response to Functionalized α-Helical Peptide
Hydrogels},
  author={Nazia Mehrban and Edgardo Abelardo and Alexandra Wasmuth and Kieran L Hudson and Leanne M. Mullen and Andrew R. Thomson and Martin Birchall and Derek N. Woolfson},
  booktitle={Advanced healthcare materials},
  year={2014}
}
α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell… CONTINUE READING