Assembly of very low density lipoproteins in mouse liver: evidence of heterogeneity of particle density in the Golgi apparatus.

@article{Swift2001AssemblyOV,
  title={Assembly of very low density lipoproteins in mouse liver: evidence of heterogeneity of particle density in the Golgi apparatus.},
  author={Larry L Swift and Klara Valyi-Nagy and Charles Rowland and Charles Harris},
  journal={Journal of lipid research},
  year={2001},
  volume={42 2},
  pages={218-24}
}
The assembly of very low density lipoproteins (VLDL) by hepatocytes is believed to occur via a two-step process. The first step is the formation of a dense phospholipid and protein-rich particle that is believed to be converted to VLDL by the addition of bulk triglyceride in a second step. Previous studies in our laboratory led us to hypothesize a third assembly step that occurs in route to or in the Golgi apparatus. To investigate this hypothesis, nascent lipoproteins were recovered from Golgi… CONTINUE READING
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