Assembly of vault-like particles in insect cells expressing only the major vault protein.

@article{Stephen2001AssemblyOV,
  title={Assembly of vault-like particles in insect cells expressing only the major vault protein.},
  author={Andrew G. Stephen and Sujna Raval-Fernandes and Tu Anh Huynh and Martha Bucio Torres and Valerie A. Kickhoefer and Leonard H Rome},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 26},
  pages={23217-20}
}
Vaults are the largest (13 megadalton) cytoplasmic ribonucleoprotein particles known to exist in eukaryotic cells. They have a unique barrel-shaped structure with 8-fold symmetry. Although the precise function of vaults is unknown, their wide distribution and highly conserved morphology in eukaryotes suggests that their function is essential and that their structure must be important for their function. The 100-kDa major vault protein (MVP) constitutes approximately 75% of the particle mass and… CONTINUE READING

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