Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles.

@article{Gonzalez1993AssemblyOT,
  title={Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles.},
  author={Susan A. Gonzalez and Jos{\'e} L Affranchino and Hans R. Gelderblom and Ars{\`e}ne Burny},
  journal={Virology},
  year={1993},
  volume={194 2},
  pages={548-56}
}
To obtain a better understanding of the processes of assembly and morphogenesis of simian immunodeficiency virus (SIV), recombinant vaccinia viruses containing regions of the gag-pol open reading frame were constructed and their intracellular expression as well as the ability of the Gag polypeptides to be released into the culture medium as constituents of virus-like particles were studied. Biochemical and electron microscopy analyses of cells infected with a recombinant expressing only the SIV… CONTINUE READING