Assembly of nebulin into the sarcomeres of avian skeletal muscle.

  title={Assembly of nebulin into the sarcomeres of avian skeletal muscle.},
  author={Carole L. Moncman and Kuan Wang},
  journal={Cell motility and the cytoskeleton},
  volume={34 3},
In developing muscle, relatively little is known about the synthesis and incorporation of the large actin binding protein, nebulin, into the sarcomere. To determine the temporal pattern of nebulin assembly into the myofibrils of differentiating skeletal muscle cells, myofibril assembly was examined by immunofluorescence microscopy. The distribution of nebulin was compared to other myofibrillar and cytoskeletal proteins (myosin, titin, actin, desmin, tubulin). At the onset of differentiation, we… CONTINUE READING
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