Assembly of centrosomal proteins and microtubule organization depends on PCM-1

@article{Dammermann2002AssemblyOC,
  title={Assembly of centrosomal proteins and microtubule organization depends on PCM-1},
  author={Alexander Dammermann and Andreas Merdes},
  journal={The Journal of Cell Biology},
  year={2002},
  volume={159},
  pages={255 - 266}
}
The protein PCM-1 localizes to cytoplasmic granules known as "centriolar satellites" that are partly enriched around the centrosome. We inhibited PCM-1 function using a variety of approaches: microinjection of antibodies into cultured cells, overexpression of a PCM-1 deletion mutant, and specific depletion of PCM-1 by siRNA. All approaches led to reduced targeting of centrin, pericentrin, and ninein to the centrosome. Similar effects were seen upon inhibition of dynactin by dynamitin, and after… CONTINUE READING

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Dynactin Is Required for Microtubule Anchoring at Centrosomes

  • The Journal of cell biology
  • 1999
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