Assembly of bacterial ribosomes.

  title={Assembly of bacterial ribosomes.},
  author={Zahra Shajani and Michael T. Sykes and James R Williamson},
  journal={Annual review of biochemistry},
The assembly of ribosomes from a discrete set of components is a key aspect of the highly coordinated process of ribosome biogenesis. In this review, we present a brief history of the early work on ribosome assembly in Escherichia coli, including a description of in vivo and in vitro intermediates. The assembly process is believed to progress through an alternating series of RNA conformational changes and protein-binding events; we explore the effects of ribosomal proteins in driving these… CONTINUE READING
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