Assembly and maturation of the flavivirus Kunjin virus appear to occur in the rough endoplasmic reticulum and along the secretory pathway, respectively.

@article{Mackenzie2001AssemblyAM,
  title={Assembly and maturation of the flavivirus Kunjin virus appear to occur in the rough endoplasmic reticulum and along the secretory pathway, respectively.},
  author={Jason M Mackenzie and Edwin G Westaway},
  journal={Journal of virology},
  year={2001},
  volume={75 22},
  pages={10787-99}
}
The intracellular assembly site for flaviviruses in currently not known but is presumed to be located within the lumen of the rough endoplasmic reticulum (RER). Building on previous studies involving immunofluorescence (IF) and cryoimmunoelectron microscopy of Kunjin virus (KUN)-infected cells, we sought to identify the steps involved in the assembly and maturation of KUN. Thus, using antibodies directed against envelope protein E in IF analysis, we found the accumulation of E within regions… CONTINUE READING
124 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 124 extracted citations

Similar Papers

Loading similar papers…