Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

@article{Zhao2011AssemblyAI,
  title={Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.},
  author={Mei Ping Zhao and D. M. C. Sano and Curtis R. Pickering and Samar A. Jasser and Ying C. Henderson and Gary L Clayman and Erich M Sturgis and Thomas J. Ow and Reuben Lotan and Thomas E. Carey and Peter G. Sacks and Jennifer R Grandis and David Sidransky and Nils Erik Heldin and Jeffrey N. Myers},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2011},
  volume={17 23},
  pages={7248-64}
}
PURPOSE Human cell lines are useful for studying cancer biology and preclinically modeling cancer therapy, but can be misidentified and cross-contamination is unfortunately common. The purpose of this study was to develop a panel of validated head and neck cell lines representing the spectrum of tissue sites and histologies that could be used for studying the molecular, genetic, and phenotypic diversity of head and neck cancer. METHODS A panel of 122 clinically and phenotypically diverse head… CONTINUE READING

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keratinocyteIs normal cell origin of diseaseSquamous cell carcinoma of skin
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
Head and neck structureIs associated anatomic site ofLeukoplakia, Oral
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
Head and neck structureIs primary anatomic site of diseaseLeukoplakia, Oral
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
Head and neck structureIs associated anatomic site ofThyroid carcinoma
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
Head and neck structureIs primary anatomic site of diseaseThyroid carcinoma
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
A panel of 122 clinically and phenotypically diverse head and neck cell lines from head and neck squamous cell carcinoma , thyroid cancer , cutaneous squamous cell carcinoma , adenoid cystic carcinoma , oral leukoplakia , immortalized primary keratinocytes , and normal epithelium was assembled from the collections of several individuals and institutions .
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