Assays of urine levels of HNL/NGAL in patients undergoing cardiac surgery and the impact of antibody configuration on their clinical performances.

@article{Cai2009AssaysOU,
  title={Assays of urine levels of HNL/NGAL in patients undergoing cardiac surgery and the impact of antibody configuration on their clinical performances.},
  author={Linjun Cai and Jan Borowiec and Shengyuan Xu and Wenyu Han and Per Venge},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2009},
  volume={403 1-2},
  pages={
          121-5
        }
}
BACKGROUND Acute kidney injury (AKI) is one of the most serious postoperative complications of cardiac surgery. The lack of early and powerful markers for AKI makes the morbidity and mortality still very high. HNL (Human neutrophil lipocalin)/NGAL (Neutrophil gelatinase-associated lipocalin) was recently shown as a novel biomarker for AKI after cardiac surgery. METHODS Serial urine samples from 59 patients undergoing cardiac surgery were analyzed by polyclonal antibody based radioimmunoassay… CONTINUE READING
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