Assays for monitoring cellular immune responses to active immunotherapy of cancer.

@article{Clay2001AssaysFM,
  title={Assays for monitoring cellular immune responses to active immunotherapy of cancer.},
  author={Timothy M. Clay and Amy C. Hobeika and Paul J. Mosca and Herbert Kim Lyerly and Michael Andew Morse},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2001},
  volume={7 5},
  pages={
          1127-35
        }
}
Numerous cancer immunotherapy strategies are currently being tested in clinical trials. Although clinical efficacy will be the final test of these approaches, the long and complicated developmental pathway for these agents necessitates evaluating immunological responses as intermediate markers of the most likely candidates for success. This has emphasized the need for assays that accurately detect and quantitate T cell-mediated, antigen-specific immune responses. This review evaluates the… CONTINUE READING
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