Assay of mucins in human tear fluid.

  title={Assay of mucins in human tear fluid.},
  author={Sandra J Spurr-Michaud and Pablo Arg{\"u}eso and Ilene K. Gipson},
  journal={Experimental eye research},
  volume={84 5},
Mucin genes, both secreted (MUC2, MUC5AC, MUC5B, MUC7) and membrane associated (MUC1, MUC4, MUC16), have been reported to be expressed by ocular surface epithelia. The purpose of this study was to comprehensively assay the mucin content of human tear fluid using multiple antibodies for each mucin and to develop a sensitive, semi-quantitative method for the assay of mucins in tears. Tear washes were obtained by instillation of saline onto the ocular surface, followed by collection from the… CONTINUE READING