Assay for evaluation of rotavirus-cell interactions: identification of an enterocyte ganglioside fraction that mediates group A porcine rotavirus recognition.

@article{Rolsma1994AssayFE,
  title={Assay for evaluation of rotavirus-cell interactions: identification of an enterocyte ganglioside fraction that mediates group A porcine rotavirus recognition.},
  author={Mark David Rolsma and Howard B. Gelberg and Mark S. Kuhlenschmidt},
  journal={Journal of virology},
  year={1994},
  volume={68 1},
  pages={
          258-68
        }
}
A virus-host cell-binding assay was developed and used to investigate specific binding between group A porcine rotavirus and MA-104 cells or porcine enterocytes. A variety of glycoconjugates and cellular components were screened for their ability to block rotavirus binding to cells. During these experiments a crude ganglioside mixture was observed to specifically block rotavirus binding. On the basis of these results, enterocytes were harvested from susceptible piglets and a polar lipid… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 62 REFERENCES

A procedure for the quantitative isolation of brain gangliosides

L. Svennerholm, P. Fredman
  • Biochim. Biophys
  • 1980
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The magnitude of the global problem of diarrhoeal disease: a ten year update

C. Bern, J. Martines, I. de Zoysa, R. I. Glass
  • Bull . W . H . O .
  • 1992
VIEW 1 EXCERPT

Carbohydrate ligands for endothelial-leukocyte adhesion molecule 1.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1991
VIEW 1 EXCERPT