Aspirin use and colorectal cancer: post-trial follow-up data from the Physicians' Health Study.

@article{Strmer1998AspirinUA,
  title={Aspirin use and colorectal cancer: post-trial follow-up data from the Physicians' Health Study.},
  author={Til St{\"u}rmer and Robert J Glynn and I Min Lee and Joann E. Manson and Julie E. Buring and Charles H. Hennekens},
  journal={Annals of internal medicine},
  year={1998},
  volume={128 9},
  pages={713-20}
}
Several recent investigations have examined whether the use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) reduces colorectal cancer incidence or mortality. Although the mechanisms behind it are not completely understood, the arachidonic acid cascade, which generates a family of bioactive lipids that modulate diverse physiologic and pathophysiologic responses, seems to play an important role in cell transformation, tumor growth, and metastasis [1]. The NSAIDs, including… CONTINUE READING

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