Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine

@inproceedings{Cao2015AspirinPB,
  title={Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine},
  author={Yu Cao and Jimin Xiong and Shenghui Mei and Fu Wang and Zhigang Zhao and Songlin Wang and Yi Liu},
  booktitle={Stem Cell Research & Therapy},
  year={2015}
}
Stem cells have great therapeutic potential due to their capacity for self-renewal and their potential for differentiating into multiple cell lineages. It has been recently shown that the host immune system has fundamental effects on the fate of transplanted mesenchymal stem cells during bone repair, where the topical administration of aspirin is capable of improving calvarial bone repair in rodents by inhibiting tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) production. This study… CONTINUE READING