Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial

@article{Halkes2006AspirinPD,
  title={Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial},
  author={P. Halkes and J. van Gijn and L. Kappelle and P. Koudstaal and A. Algra},
  journal={The Lancet},
  year={2006},
  volume={367},
  pages={1665-1673}
}
BACKGROUND Results of trials of aspirin and dipyridamole combined versus aspirin alone for the secondary prevention of vascular events after ischaemic stroke of presumed arterial origin are inconsistent. Our aim was to resolve this uncertainty. METHODS We did a randomised controlled trial in which we assigned patients to aspirin (30-325 mg daily) with (n=1363) or without (n=1376) dipyridamole (200 mg twice daily) within 6 months of a transient ischaemic attack or minor stroke of presumed… Expand
Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk
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Aspirin at any dose above 30 mg offers only modest protection after cerebral ischaemia.
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