Aspirin-induced microscopic surface changes stimulate thrombopoiesis in rat megakaryocytes.

Abstract

During the process of thrombopoiesis, invaginations of the plasma membrane occur in megakaryocytes. Since acetylsalicylic acid (aspirin), the most commonly used anti-inflammatory and antiplatelet drug, interacts with the lipid bilayers of the plasma membranes, this drug would affect the process of thrombopoiesis. In the present study, employing a standard… (More)
DOI: 10.1177/1076029612461845

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