Aspirin in chronic cardiovascular disease and acute myocardial infarction.


The ability of low-dose aspirin to irreversibly inhibit platelet-dependent cyclooxygenase provides a biologic mechanism to explain why this drug may decrease the risk of thrombotic cardiovascular events. Observational epidemiologic studies, both case-control and cohort, have suggested that aspirin might reduce the risk of cardiovascular disease by… (More)


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