Aspirin-exacerbated respiratory disease: update on pathogenesis and desensitization.

@article{White2012AspirinexacerbatedRD,
  title={Aspirin-exacerbated respiratory disease: update on pathogenesis and desensitization.},
  author={Andrew A. White and Donald D. Stevenson},
  journal={Seminars in respiratory and critical care medicine},
  year={2012},
  volume={33 6},
  pages={
          588-94
        }
}
Aspirin-exacerbated respiratory disease (AERD) is a unique syndrome of airway inflammation that frequently occurs in patients with nasal polyposis, chronic sinusitis, and asthma. These patients tend to have progressive and recalcitrant sinus disease requiring frequent surgical intervention and in many cases systemic corticosteroids. Much about the pathogenesis of AERD remains unclear, but environmental factors likely play a prominent role in its development. Avoidance of aspirin or nonsteroidal… CONTINUE READING
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