Aspirin as a risk factor for hemorrhage in patients with head injuries

@article{Reymond1992AspirinAA,
  title={Aspirin as a risk factor for hemorrhage in patients with head injuries},
  author={Marc Andr{\'e} Reymond and German A. Marbet and Ernst W. Radii and Othmar Gratzl},
  journal={Neurosurgical Review},
  year={1992},
  volume={15},
  pages={21-25}
}
The role of aspirin as a risk factor in the occurrence of intracranial bleeding following head injury was investigated. Chronic subdural hematoma appears to be a suitable model for the evaluation of risk factors in the development of hemorrhage. The most common risk factors found in our study were, apart from age, chronic alcohol abuse (28%), consumption of cumarin-derivates (21%), aspirin (13%), and heparin (5%). A patient undergoing aspirin treatment must be considered at risk of development… 
Predictors of mortality in trauma patients with intracranial hemorrhage on preinjury aspirin or clopidogrel.
TLDR
There is high mortality rate associated with ASA or clopidogrel or both in elderly patients who have head trauma resulting in ICH and the presenting GCS and initial grade of CT scan are most predictive of death.
Risk factors and outcome of primary intracerebral hemorrhage with special reference to aspirin
TLDR
Use of aspirin appeared to be a significant risk factor for ICH in the subjects with a history of epistaxis, and enhanced thromboxane and prostacyclin biosynthesis were observed in the acute phase and 3 months after ICH.
RISK FACTORS AND OUTCOME OF PRIMARY INTRACEREBRAL HEMORRHAGE WITH SPECIAL REFERENCE TO ASPIRIN PERTTI SALOHEIMO
TLDR
Use of aspirin appeared to be a significant risk factor for ICH in the subjects with a history of epistaxis, and enhanced thromboxane and prostacyclin biosynthesis were observed in the acute phase and 3 months after ICH.
Low-dose aspirin prophylaxis and risk of intracranial hemorrhage in patients older than 60 years of age with mild or moderate head injury: a prospective study.
TLDR
It is concluded that LDA does not increase surgically relevant parenchymal or meningeal bleeding following moderate and minor head injury in patients older than 60 years of age.
Aspirin and the risk of intracranial complications following head injury
TLDR
It is concluded that aspirin may increase the risk of developing intracranial complications following head injury and more research is needed.
Spontaneous and iatrogenic dehydration in the elderly alone or in combination with antiplatelet/anticoagulation agents and risk of subdural hematoma
TLDR
Elderly population is prone to dehydration and overzealous use of diuretics especially in combination with anticoagulation or antiplatelet therapy can contribute to the development of subdural hematomas, both spontaneous and traumatic.
Incidence and predictors of intracranial hemorrhage after minor head trauma in patients taking anticoagulant and antiplatelet medication.
TLDR
Despite a presenting GCS score of 15, patients with minor head injury from the trauma registry at the authors' institution taking anticoagulation or antiplatelet therapy have a high incidence of intracranial hemorrhage especially after reported loss of consciousness.
Secondary intracranial hemorrhage after mild head injury in patients with low-dose acetylsalicylate acid prophylaxis.
TLDR
Patients with LDA prophylaxis after mild head injury with negative primary head CT should be subjected to RRHCT within 12 hours to 24 hours to accurately identify SIHE.
Effect of antiplatelet/anticoagulant agents in elderly patients of chronic subdural hematoma: a case control study from a tertiary care centre
TLDR
Anticoagulant and antiplatelet therapy have a significant association with an increased risk of chronic subdural haematoma (CSDH), and this association appears even stronger in those patients under anticoagULant therapy, who develop a CSDH in the absence of a recent trauma.
Predicting intracranial lesions by antiplatelet agents in subjects with mild head injury
TLDR
Antiplatelet drugs need to be considered in future prediction models on mild head injury, considering their increasing use and progressive ageing of the trauma population.
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