Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trial

@article{Es2002AspirinAC,
  title={Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trial},
  author={Robert F van Es and Jan Jonker and Freek W. A. Verheugt and Jaap Willem Deckers and for the Antithrombotics in the Secondary Prevention of Group},
  journal={The Lancet},
  year={2002},
  volume={360},
  pages={109-113}
}
BACKGROUND Antiplatelet treatment with aspirin and oral anticoagulants reduces recurrence of ischaemic events after myocardial infarction. We aimed to investigate which of these drugs is more effective in the long term after acute coronary events, and whether the combination of aspirin and oral anticoagulants offers greater benefit than either of these agents alone, without excessive risk of bleeding. METHODS In a randomised open-label trial in 53 sites, we randomly assigned 999 patients to… CONTINUE READING

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