Aspirin and Reye Syndrome

@article{Schrr2007AspirinAR,
  title={Aspirin and Reye Syndrome},
  author={Karsten Schr{\"o}r},
  journal={Pediatric Drugs},
  year={2007},
  volume={9},
  pages={195-204}
}
  • K. Schrör
  • Published 2007
  • Medicine, Biology
  • Pediatric Drugs
Reye syndrome is an extremely rare but severe and often fatal disease. Death occurs in about 30–40% of cases from brainstem dysfunction. The disease typically is preceded by a viral infection with an intermediate disease-free interval of 3–5 days. The biochemical explanation for Reye-like symptoms is a generalized disturbance in mitochondrial metabolism, eventually resulting in metabolic failure in the liver and other tissues.The etiology of ‘classical’ Reye syndrome is unknown. Hypothetically… 

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  • Medicine, Biology
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  • 2019
This, to the authors' knowledge, appears to be the first report of a low-dose aspirin rechallenge 30 years later in life in an adult patient with a history of Reye syndrome while receiving aspirin therapy during childhood.

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A 7-year-old child was temporarily associated with the novel coronavirus disease which evolved into serious illness, with coronary aneurysm, using human immunoglobulin and acetylsalicylic acid, in which clinical manifestations including hepatitis, convulsions, and coma were aggravated with Reye's syndrome.

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  • L. NinoveL. Daniel R. Charrel
  • Medicine
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2011
In the current situation of the novel A/H1N1 virus pandemic, it is of high importance to emphasize the risks associated with salicylate intake to avoid the reappearance of Reye's syndrome.

Influenza-associated central nervous system dysfunction: a literature review.

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  • Medicine, Psychology
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  • 2008

The neurological sequelae of pandemics and epidemics

All the pandemics, large and important epidemics of human history in which neurological manifestations are evident are reviewed, and the possible physiological processes that leads to the adverse sequelae caused or triggered by those pathogens are described.
...

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