Aspirin, NSAIDs, and risk of prostate cancer: results from the REDUCE study.

  title={Aspirin, NSAIDs, and risk of prostate cancer: results from the REDUCE study.},
  author={Adriana C Vidal and Lauren E. Howard and Daniel M Moreira and Ramiro Castro-Santamaria and Gerald L. Andriole and Stephen J. Freedland},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={21 4},
PURPOSE A recent meta-analysis showed that aspirin was associated with reduced prostate cancer risk. As anti-inflammatory medications lower PSA levels, whether these findings reflect reduced prostate cancer detection or lower prostate cancer risk is unknown. We tested the association between aspirin and nonaspirin NSAID use on prostate cancer diagnosis in REDUCE, where all men received biopsies at 2 and 4 years largely independent of PSA. REDUCE tested dutasteride for prostate cancer risk… CONTINUE READING
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