Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project.

Abstract

We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus in submerged fermentation (SmF) and SSF are compared and we observe a number of differences correlated with the different growth conditions. First, the aerial hyphae which occur only in SSFs are mainly responsible for oxygen uptake. Second, SSF is characterised by gradients in temperature, water activity and nutrient concentration, and inside the hyphae different polyols are accumulating. Third, pelleted growth in SmF and mycelial growth in SSF show different gene expression and protein secretion patterns. With this approach we aim to expand our knowledge of mechanisms of fungal growth on solid substrates and to exploit the biotechnological applications.

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@article{Biesebeke2002AspergillusOI, title={Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project.}, author={Rob te Biesebeke and George J. G. Ruijter and Yovita S P Rahardjo and Marisca J Hoogschagen and Margreet Heerikhuisen and Ana Levin and Kenneth G A van Driel and Maarten A I Schutyser and Jan Dijksterhuis and Yang Zhu and Frans J Weber and Willem M de Vos and Kees A M J J van den Hondel and Arjen Rinzema and Peter J. Punt}, journal={FEMS yeast research}, year={2002}, volume={2 2}, pages={245-8} }