Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum.

@article{Giacchino2006AspergillusGE,
  title={Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum.},
  author={Mareva Giacchino and Nadia Chiapello and Stefania Bezzio and Franca Fagioli and Paola Saracco and Alda Alfarano and Vincenza Martini and Giuseppe Cimino and Pietro Di Martino and Corrado Girmenia},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 9},
  pages={3432-4}
}
We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data seem to suggest that G. capitatum produces a soluble antigen that is cross-reactive with Aspergillus… CONTINUE READING

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